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MR-guided adaptive radiotherapy

The MR-linac is a radiation machine with an MRI inside it, so the plan is adjusted to where the tumour is that very day.

Elekta Unity and ViewRay MRIdian enable daily online adaptation and gating on soft-tissue targets (pancreas, prostate, liver). MIRAGE trial showed reduced toxicity in prostate SBRT. Biology-guided radiotherapy (RefleXion, PET-guided) is a parallel approach.

Schematic · not to scale
MRI bore · Linac gantry · Daily-adapted target

How it works

Integrated MRI acquires images during setup and delivery; plan re-optimised in minutes.

Strengths
  • Tighter margins, dose escalation in pancreas
Limitations
  • Slow throughput
  • Cost

Latest papers

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Literature trend423 papers in the last 12 months+7% vs prior 12How this is computed
Latest papers · live from Europe PMC
Open in Europe PMC

Query for this technology: (TITLE:"MR-linac" OR ABSTRACT:"MR-linac" OR TITLE:"MR-guided radiotherapy" OR ABSTRACT:"MR-guided radiotherapy" OR TITLE:"adaptive radiotherapy" OR ABSTRACT:"adaptive radiotherapy"). Results are unfiltered search hits about MR-guided adaptive radiotherapy, not a curated reading list.

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