A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
A phase 3 trial of Crisantaspase, Asparaginase, Cytarabine, Daunorubicin, Dexrazoxane, Etoposide, Fludeoxyglucose F-18, Gemtuzumab ozogamicin, Gilteritinib, CPX-351, Methotrexate and Mitoxantrone in Acute myeloid leukaemia, run by Children's Oncology Group, now recruiting.
Overview
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations is a phase 3 interventional study registered as NCT04293562 by Children's Oncology Group, with 1400 participants planned, started 2020-07-21 and due to reach its primary completion in 2029-06-30. Interventions recorded: Allogeneic Hematopoietic Stem Cell Transplantation, Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Cytarabine, Daunorubicin Hydrochloride, Dexrazoxane Hydrochloride, Etoposide, Fludeoxyglucose F-18, Gemtuzumab Ozogamicin, Gilteritinib Fumarate, Liposome-encapsulated Daunorubicin-Cytarabine, Magnetic Resonance Imaging, Methotrexate, Mitoxantrone Hydrochloride, Positron Emission Tomography, Questionnaire Administration, Therapeutic Hydrocortisone. Conditions recorded: Acute Myeloid Leukemia.
Linked to the drug Crisantaspase because the registry names it among its interventions and Acute myeloid leukaemia among its conditions. Registry record only: no result has been read by an editor.
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