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Cancers
Philadelphia chromosome-like acute lymphoblastic leukaemia (Ph-like or BCR::ABL1-like ALL)
Data

Cancers·Philadelphia chromosome-like acute lymphoblastic leukaemia (Ph-like or BCR::ABL1-like ALL)

DataPhiladelphia chromosome-like acute lymphoblastic leukaemia (Ph-like or BCR::ABL1-like ALL)

Back to the Philadelphia chromosome-like acute lymphoblastic leukaemia hub →39 connected records

Every connected record, the notes, the JSON, Markdown and RDF twins, and where the record came from and when it was checked.

Overview What it is Finding it Treating it Evidence The science Where you are Living with it What is coming Data

Data

Related pages

39

Direct links plus the targets, companies, and technologies of this cancer's products.

Similar pages

not linked directly; found by shared links

Cancer
Acute myeloid leukaemia in children
Shares Multiparameter flow cytometry MRD, St. Jude Children's Research Hospital, Infant acute lymphoblastic leukaemia (KMT2A-rearranged, under one year), Allogeneic stem cell transplantation and the tags subtype-page, paediatric.
Cancer
Multisystem Langerhans cell histiocytosis (with or without risk-organ involvement)
Shares Allogeneic stem cell transplantation, Small-molecule kinase inhibitors and the tags subtype-page, paediatric.
Cancer
Low-risk neuroblastoma (INRG very low and low risk, including stage MS)
Shares Children's Oncology Group (COG) and the tags subtype-page, paediatric.
Cancer
Intermediate-risk neuroblastoma
Shares Children's Oncology Group (COG) and the tags subtype-page, paediatric.
Cancer
Single-system Langerhans cell histiocytosis (bone, skin or one other organ)
Shares Small-molecule kinase inhibitors and the tags subtype-page, paediatric.
Cancer
High-risk neuroblastoma
Shares Children's Oncology Group (COG) and the tags subtype-page, paediatric.
Cancer
WNT-activated medulloblastoma
Shares St. Jude Children's Research Hospital, Children's Oncology Group (COG) and the tags subtype-page, paediatric.
Cancer
Group 3 and group 4 medulloblastoma (non-WNT/non-SHH)
Shares St. Jude Children's Research Hospital, Children's Oncology Group (COG) and the tags subtype-page, paediatric.

technologies

7

Allogeneic stem cell transplantation CAR-T cell therapy Comprehensive genomic profiling Multiparameter flow cytometry MRD NGS-based MRD (clonoSEQ and molecular MRD)Small-molecule kinase inhibitors T-cell engagers (bispecific)

targets

10

ABL1 BCR::ABL1 (Philadelphia chromosome)CD19 CD3 DDR2 receptor kinase Erythropoietin receptor (EPOR)JAK1 JAK2 KIT PDGFRB

drugs

5

ApprovedBispecific T-cell engager (CD19×CD3)

Blinatumomab · Blincyto

ApprovedSmall-molecule kinase inhibitor (BCR::ABL1, SRC)

Dasatinib · Sprycel

ApprovedSmall-molecule kinase inhibitor (BCR-ABL, KIT, PDGFRA)

Imatinib · Gleevec

ApprovedSmall-molecule JAK1/JAK2 inhibitor

Ruxolitinib · Jakafi / Jakavi

ApprovedCAR-T (CD19)

Tisagenlecleucel · Kymriah

companies

5

Amgen Bristol Myers Squibb Incyte Natco Pharma Novartis

institutions

2

Children's Oncology Group (COG)St. Jude Children's Research Hospital

terms

4

B-ALL risk groups (NCI criteria, ETV6::RUNX1, hyperdiploidy, hypodiploidy, iAMP21, IKZF1, CNS status)Minimal / molecular residual disease (MRD)Ph-like (BCR::ABL1-like) acute lymphoblastic leukaemia Philadelphia chromosome (Ph+, BCR::ABL1)

trials

2

AALL1521 Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)

key papers

4

A subtype of childhood acute lymphoblastic leukaemia with poor outcome: genome-wide classification study (BCR-ABL1-like ALL)Acute lymphoblastic leukaemia in children (review)Deletion of IKZF1 and prognosis in acute lymphoblastic leukaemia Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukaemia

Machine-readable versions

The same record for scripts and assistants; checked 2026-09-17. Data CC BY-NC 4.0, attribute “Data from OnCo (onco.cc)”.

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Not yet reviewedNeeds expert (clinical) and patient advocate review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link cancer subtypes to their siblings and name parents i… · diff · file

Wikipedia

Acute lymphoblastic leukemia

Sources & links

Wikipedia: Acute lymphoblastic leukaemia
NCI PDQ: Childhood ALL Treatment

subtype-page paediatric

Data

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