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Levetiracetam is an anti-seizure medicine. After CAR-T cell therapy it is the recommended treatment for seizures, and some people at high risk of nerve side effects take it to prevent them.
The Keppra label covers partial-onset seizures from 1 month of age and, as adjunctive therapy, myoclonic seizures in juvenile myoclonic epilepsy and primary generalised tonic-clonic seizures. SITC 2020: "To manage seizures in patients treated with CAR T cell therapies, levetiracetam is recommended (LE: 4)"; there is insufficient evidence for prophylaxis in everyone, but "in patients deemed to be at high-risk of developing neurotoxicity ... prophylactic levetiracetam may be considered". The NDA was first approved on 30 November 1999.
An antiepileptic that binds synaptic vesicle protein SV2A.
1.Levetiracetam slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 1999 | Partial-onset seizures; adjunctive treatment of myoclonic and primary generalised tonic-clonic seizures · Year is the Keppra NDA 021035 approval (Drugs@FDA) |
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Query for this drug: (TITLE:"Levetiracetam" OR ABSTRACT:"Levetiracetam" OR TITLE:"Keppra" OR ABSTRACT:"Keppra") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Levetiracetam, not a curated reading list.
Shares CAR-T cell therapy and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
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