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Tenofovir is an antiviral tablet for hepatitis B and HIV. Someone with current or past hepatitis B who needs certain cancer treatments takes it to stop the virus flaring up.
The Viread (tenofovir disoproxil fumarate) label covers HIV-1 infection with other antiretrovirals and chronic hepatitis B; the Vemlidy (tenofovir alafenamide) label covers chronic hepatitis B with compensated liver disease. ASCO's 2020 provisional clinical opinion on hepatitis B and cancer summarises guidance that patients with chronic infection or past exposure receiving higher-risk chemotherapy "require antiviral prophylaxis with tenofovir or entecavir". Viread was first approved on 26 October 2001 and Vemlidy on 10 November 2016.
A nucleotide analogue that inhibits hepatitis B virus and HIV-1 reverse transcriptase.
1.Tenofovir (disoproxil and alafenamide) slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 2001 | Viread: HIV-1 infection and chronic hepatitis B · NDA 021356 (Drugs@FDA) |
| US | 2016 | Vemlidy: chronic hepatitis B with compensated liver disease · NDA 208464 (Drugs@FDA) |
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Query for this drug: (TITLE:"Tenofovir" OR ABSTRACT:"Tenofovir" OR TITLE:"disoproxil and alafenamide" OR ABSTRACT:"disoproxil and alafenamide" OR TITLE:"Viread" OR ABSTRACT:"Viread" OR TITLE:"Vemlidy" OR ABSTRACT:"Vemlidy" OR TITLE:"tenofovir disoproxil fumarate" OR ABSTRACT:"tenofovir disoproxil fumarate" OR TITLE:"TDF" OR ABSTRACT:"TDF") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Tenofovir (disoproxil and alafenamide), not a curated reading list.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
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