Loading
Warfarin is an older blood-thinning tablet that needs regular blood tests. For a clot in someone with cancer, guidelines now prefer heparin injections or the newer tablets, but warfarin still has a place, for example with severe kidney failure.
The warfarin label covers prophylaxis and treatment of venous thrombosis and pulmonary embolism, thromboembolism with atrial fibrillation or valve replacement, and risk reduction after myocardial infarction. ITAC 2022 prefers LMWHs over vitamin K antagonists for treating VTE in cancer when creatinine clearance is at least 30 mL/min (1A); with severe renal failure (creatinine clearance below 30 mL/min) it suggests unfractionated heparin followed by early vitamin K antagonists, or LMWH adjusted to anti-Xa levels (guidance, in the absence of data). The Coumadin NDA was approved on 8 June 1954.
A vitamin K antagonist: reduces the liver's production of active vitamin K-dependent clotting factors; dosing is monitored by the INR.
1.Warfarin slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 1954 | Prophylaxis and treatment of venous thrombosis and pulmonary embolism; thromboembolism with atrial fibrillation or valve replacement; after myocardial infarction · Year is the Coumadin NDA 009218 approval (Drugs@FDA) |
Country and place are remembered in this browser only. A postcode is sent to OpenStreetMap's Nominatim service to find coordinates when you press the button; nothing else leaves your device.
Query for this drug: (TITLE:"Warfarin" OR ABSTRACT:"Warfarin" OR TITLE:"Coumadin" OR ABSTRACT:"Coumadin" OR TITLE:"warfarin sodium" OR ABSTRACT:"warfarin sodium" OR TITLE:"vitamin K antagonist" OR ABSTRACT:"vitamin K antagonist") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Warfarin, not a curated reading list.
Shares Tinzaparin, Enoxaparin, Venous thromboembolism (VTE), Cancer-associated thrombosis prevention and treatment and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Enoxaparin, Venous thromboembolism (VTE), Cancer-associated thrombosis prevention and treatment and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Enoxaparin, Venous thromboembolism (VTE), Cancer-associated thrombosis prevention and treatment and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Enoxaparin, Venous thromboembolism (VTE), Cancer-associated thrombosis prevention and treatment and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/