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Edoxaban is a blood-thinning tablet. For a clot in someone with cancer it is started after at least five days of heparin injections.
The Savaysa label covers stroke prevention in non-valvular atrial fibrillation and treatment of DVT and pulmonary embolism "following 5 to 10 days of initial therapy with a parenteral anticoagulant". ITAC 2022 allows edoxaban for initial treatment of VTE in cancer when started after at least 5 days of parenteral anticoagulation, in people without a high risk of gastrointestinal or genitourinary bleeding (1A), and lists edoxaban with rivaroxaban and apixaban among the DOACs recommended for maintenance (1A), with caution in gastrointestinal cancers. The NDA was first approved on 8 January 2015.
A direct, oral inhibitor of activated factor X.
1.Edoxaban slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 2015 | Stroke prevention in non-valvular atrial fibrillation; treatment of DVT and PE after 5 to 10 days of parenteral anticoagulation · Year is the original NDA 206316 approval (Drugs@FDA) |
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Query for this drug: (TITLE:"Edoxaban" OR ABSTRACT:"Edoxaban" OR TITLE:"Savaysa" OR ABSTRACT:"Savaysa" OR TITLE:"Lixiana" OR ABSTRACT:"Lixiana") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Edoxaban, not a curated reading list.
Shares Apixaban, Enoxaparin, Venous thromboembolism (VTE), Cancer-associated thrombosis prevention and treatment and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Enoxaparin, Venous thromboembolism (VTE), Cancer-associated thrombosis prevention and treatment and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Enoxaparin, Venous thromboembolism (VTE), Cancer-associated thrombosis prevention and treatment and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
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