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A tumour changes over time as its cells acquire mutations and the fittest clones take over, which is why cancers relapse and resist treatment.
Somatic evolution, as Wikipedia summarises it, is the accumulation of mutations and epimutations in body cells over a lifetime and the effect of those changes on the cells' fitness; Vogelstein's colon cancer studies first showed it and the framework now explains progression, metastasis and resistance. Tracking clones through time from serial biopsies or blood is one of the mechanisms cancer models aim to learn.
Showing the technology this term belongs to: Tumour clonal evolution tracking.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.