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Everything OnCo dates to 1990: 45 entries, 23 landmarks, 8 technologies, 4 journals founded and 3 approvals. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.
45 dated entries in OnCo fall in 1990: 23 landmarks, 8 technologies, 4 journals founded, 3 approvals, 3 companies founded, 2 papers and 2 papers listed on people's pages.
Of those, 45 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.
Everything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.
The approvals rows on treatment records: region, year and indication.
Persistent or recurrent ovarian cancer after first-line cisplatin or alkylating agent combinations
Adult acute myeloid leukaemia, as a component of combination induction chemotherapy
Carcinoma in situ of the bladder (TICE BCG)
The publication year on key paper records.
Fearon ER, Vogelstein B. Cell.
Moertel CG, Fleming TR, Macdonald JS, et al. New England Journal of Medicine.
The history entries editors wrote on cancer records: the dated turning points of each disease.
Colorectal cancer. Fluorouracil with levamisole improved survival after resection of node-positive colon cancer (1990); MSH2 and MLH1 were cloned in 1993.
Anaplastic thyroid cancer
Cancer of unknown primary, favourable subsets
Non-muscle-invasive bladder cancer
Bladder & urothelial cancer
Chronic myeloid leukaemia (CML). Daley, Van Etten and Baltimore demonstrate the fusion kinase is sufficient to cause a CML-like disease.
Chronic myeloid leukaemia, chronic phase
Unresectable stage III non-small-cell lung cancer
Germ cell tumours of childhood and adolescence (extracranial and CNS). UKCCSG shows carboplatin can replace cisplatin in children with less hearing and kidney toxicity.
Medulloblastoma
Hairy cell leukaemia
Oesophageal cancer
Advanced and metastatic adrenocortical carcinoma (ENSAT stage IV or unresectable)
Gastric & gastro-oesophageal junction cancer. Shift to early-stage diagnosis and 5-year survival >60%.
Burkitt lymphoma. French SFOP protocol cures most children including stage IV.
Malignant peripheral nerve sheath tumour (MPNST)
Brain metastases (secondary brain tumours)
Acute lymphoblastic leukaemia. NCI/Rome criteria (age, white count); paediatric cooperative groups reach ~70% cure.
Vulvar cancer
Hepatoblastoma
Adolescent and young adult cancers (ages 15 to 39)
Diffuse midline glioma, H3 K27-altered (including DIPG). Radiation-only remains standard as more than 200 agents fail to add benefit.
Wilms tumour (nephroblastoma). First Wilms tumour gene; also links to WAGR and Denys-Drash.
The since year on technology records: first use in humans or first approval, as the record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
The founded year on company records.
Chandler, AZ
Tokyo
Budapest
The founded year on journal records.
Elsevier
Springer
Oxford University Press
Elsevier (Academic Press)
The selected publications each biography lists, which is a reading of that person rather than a reading of the year.
Immunology Today
Journal of Clinical Oncology