OnCo

Create your OnCo account

One account keeps your watchlist, saved views and cancer choice in sync across your devices, and lets OnCo alert you when a trial or treatment you follow changes. No password: we email you a sign-in link.

Account creation is being switched on. Until then, press Watch on any page and your list stays in this browser.

Living with cancer· Appointment prep

Appointment sheet: Metastatic castration-resistant prostate cancer

One page to bring and write on: your details, the questions for Metastatic castration-resistant prostate cancer plus your own, the words you may hear, what to bring, the treatments the standard of care names, and room for the answers and agreed next steps. What you type stays in this browser. Print it or save it as a PDF. New to all this? Start with the first 60 days. Orientation, not medical advice.

Tick the questions to print

All of this cancer's questions start ticked. Untick what does not apply; ticks are kept in this browser. .

Your own questions

Shared with the prep pack, so questions you add there appear here too.

Print or save as PDF

Use (or Ctrl+P, Cmd+P on a Mac). To keep a copy, choose Save as PDF as the destination in the print dialog. Only the sheet prints; the controls stay on screen. Your typed notes print where you typed them; empty fields print as ruled lines to write on.

Appointment sheet

Metastatic castration-resistant prostate cancer

Prepared with OnCo (onco.cc/prep/prostate-mcrpc/). Orientation, not medical advice; your team knows your case.

My details

Name
Date of appointment
Hospital and clinician
Who is coming with me

What I know, what is unclear, changes to discuss

Saved in this browser
What I know so far
What is unclear to me
Changes since last time

My questions

23 on the sheet
Newly diagnosed
  1. 1.What is my exact diagnosis, stage, and grade, and which tests established them?
  2. 2.Which biomarkers have been tested on my tumour (for example Tumour and germline HRR genes, PSMA PET uptake and FDG discordance, Mismatch repair deficiency and tumour mutational burden, PSA and alkaline phosphatase, Circulating tumour DNA), and what were the results?
  3. 3.Which subtype is my cancer, and does that change the recommended treatment?
  4. 4.Is germline (inherited) genetic testing recommended for me or my family?
First line, androgen receptor pathway inhibitor-naive
  1. 5.For my situation (first line, androgen receptor pathway inhibitor-naive), which of the standard options do you recommend and why?
  2. 6.Am I a candidate for Abiraterone acetate, Enzalutamide, Olaparib or related drugs, and what side effects should I expect?
  3. 7.How do the results of PROpel and TALAPRO-2 apply to someone like me?
After an androgen receptor pathway inhibitor
  1. 8.For my situation (after an androgen receptor pathway inhibitor), which of the standard options do you recommend and why?
  2. 9.Am I a candidate for Docetaxel, Olaparib, Rucaparib or related drugs, and what side effects should I expect?
  3. 10.How do the results of PROfound and PSMAfore apply to someone like me?
After docetaxel
  1. 11.For my situation (after docetaxel), which of the standard options do you recommend and why?
  2. 12.Am I a candidate for Lutetium-177 vipivotide tetraxetan, Cabazitaxel, Radium-223 dichloride, and what side effects should I expect?
  3. 13.How do the results of VISION and ALSYMPCA apply to someone like me?
Bone health
  1. 14.For my situation (bone health), which of the standard options do you recommend and why?
  2. 15.Am I a candidate for Denosumab, Zoledronic acid, and what side effects should I expect?
Phase 3 options
  1. 16.For my situation (phase 3 options), which of the standard options do you recommend and why?
  2. 17.Am I a candidate for Actinium-225 PSMA agents, Xaluritamig, Mevrometostat or related drugs, and what side effects should I expect?
  3. 18.How do the results of AlphaBreak (FPI-2265) & AcTION (225Ac-PSMA-617) and XALute apply to someone like me?
Any stage
  1. 19.Are there clinical trials I could join, for example of Actinium-225 PSMA agents, Xaluritamig, Mevrometostat, 177Lu-PSMA-I&T?
  2. 20.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
  3. 21.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
  4. 22.I read that “The best sequence of radioligand, PARP inhibitor and chemotherapy is untested”. How does that affect my plan?
  5. 23.I read that “Actinium-225 supply and the lack of alpha-emitter dosimetry”. How does that affect my plan?

Tests and results to bring

Biomarker results to ask for: Tumour and germline HRR genes (BRCA2 above all), PSMA PET uptake and FDG discordance, Mismatch repair deficiency and tumour mutational burden, PSA and alkaline phosphatase, Circulating tumour DNA (AR amplification, BRCA2 reversion), AR-V7 in circulating tumour cells (research).

Scans and tests linked to this cancer: PSMA PET.

Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.

The treatments I may be offered

From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.

Answers and next steps

Saved in this browser
What I was told
Agreed next steps, dates and who to call