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Everything OnCo dates to 1995: 50 entries, 12 landmarks, 10 approvals, 7 journals founded and 6 papers. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.
50 dated entries in OnCo fall in 1995: 12 landmarks, 10 approvals, 7 journals founded, 6 papers, 5 companies founded, 5 papers listed on people's pages and 5 technologies.
Of those, 50 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.
Everything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.
The approvals rows on treatment records: region, year and indication.
Reduction of cumulative cisplatin renal toxicity in advanced ovarian cancer
Advanced breast cancer in postmenopausal women after tamoxifen
Advanced prostate cancer; 150 mg for locally advanced
Metastatic prostate cancer with LHRH analogue
Reduction of doxorubicin cardiomyopathy in women with metastatic breast cancer after 300 mg/m2 cumulative dose (Zinecard)
Adjuvant high-risk melanoma (high-dose)
Osteolytic bone metastases of breast cancer and osteolytic lesions of multiple myeloma, with antineoplastic therapy
AIDS-related Kaposi sarcoma after prior chemotherapy (Doxil, NDA 050718)
Palliation of completely or partially obstructing oesophageal cancer; later endobronchial NSCLC and Barrett's high-grade dysplasia
Induction of remission in APL (t(15;17)/PML-RARA)
The publication year on key paper records.
Non-small Cell Lung Cancer Collaborative Group. BMJ.
Visakorpi T, Hyytinen E, Koivisto P, et al. Nature Genetics.
Markowitz S, Wang J, Myeroff L, et al. Science.
Klimstra DS, Wenig BM, Adair CF, Heffess CS. American Journal of Surgical Pathology.
Taplin ME, Bubley GJ, Shuster TD, et al. New England Journal of Medicine.
Grever M, Kopecky K, Foucar MK, et al. Journal of Clinical Oncology.
The history entries editors wrote on cancer records: the dated turning points of each disease.
Male breast cancer. Wooster and colleagues identify BRCA2; male breast cancer is one of its hallmark phenotypes.
Prostate cancer. Visakorpi found androgen receptor gene amplification in 7 of 23 tumours recurring on androgen deprivation and in none of the pre-treatment samples from the same me...
Lung cancer (all types). 9,387 patients from 52 randomised trials: a 27 percent reduction in the risk of death when chemotherapy was added to supportive care, and 5 percent absolut...
Colorectal cancer. TGFBR2, the growth brake, is destroyed by slippage in a short repeat in mismatch repair deficient colon cancer lines.
Indolent and smouldering systemic mastocytosis
Kaposi sarcoma
Resectable stage I to III non-small-cell lung cancer
Metastatic cancer (cancer that has spread). Hellman and Weichselbaum argue that some patients have a limited metastatic state that local treatment could control, the idea SABR-COME...
Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei
Peritoneal mesothelioma. Peritonectomy procedures and heated intraperitoneal chemotherapy applied to peritoneal surface malignancy.
Appendiceal cancer and pseudomyxoma peritonei
Prostate cancer. In the same year as the amplification finding, ligand-binding-domain mutations that let progesterone, oestrogen and the antiandrogen itself switch the receptor on...
The since year on technology records: first use in humans or first approval, as the record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
First use in humans or first approval, as the technology record states it.
The founded year on company records.
United States (seat not stated)
Madrid
Louisville, Colorado
Lianyungang, Jiangsu
Barcelona
The founded year on journal records.
American Association for Cancer Research
SAGE Publications
Lippincott Williams & Wilkins (Wolters Kluwer)
Springer Nature
Frontiers Media SA
Wiley (Hindawi)
Elsevier
The selected publications each biography lists, which is a reading of that person rather than a reading of the year.
Blood
Nature Medicine
Journal of Immunology
Science
Journal of Pediatric Surgery