OnCo

328 cancer pages under 15 organ systems and 4 histology groupings, joined by 376 edges in 4 layers. 275 are subtypes of a broader cancer, and 47 sit under more than one node, which is why this is a graph and not a tree.

Cancer mapLayered directed graph: organ systems and histology groupings on the left, cancers in the middle, subtypes on the right. Each node links to its page; the same structure follows as a nested list.Haematologic62328819061Haematologic: 623 trials, 288 products, 190 approved, 61 ideas (with 8 beneath)Gastrointestinal618243107164Gastrointestinal: 618 trials, 243 products, 107 approved, 164 ideas (with 11 beneath)Paediatric1031009020Paediatric: 103 trials, 100 products, 90 approved, 20 ideas (with 19 beneath)Gynaecologic2631206757Gynaecologic: 263 trials, 120 products, 67 approved, 57 ideas (with 7 beneath)Genitourinary3691769894Genitourinary: 369 trials, 176 products, 98 approved, 94 ideas (with 7 beneath)Head and neck138824636Head and neck: 138 trials, 82 products, 46 approved, 36 ideas (with 5 beneath)Sarcoma84947037Sarcoma: 84 trials, 94 products, 70 approved, 37 ideas (with 1 beneath)Endocrine58715420Endocrine: 58 trials, 71 products, 54 approved, 20 ideas (with 7 beneath)Lung66224211294Lung: 662 trials, 242 products, 112 approved, 94 ideas (with 3 beneath)Breast25916287123Breast: 259 trials, 162 products, 87 approved, 123 ideas (with 1 beneath)Skin163955945Skin: 163 trials, 95 products, 59 approved, 45 ideas (with 3 beneath)Central nervous system116826431Central nervous system: 116 trials, 82 products, 64 approved, 31 ideas (with 2 beneath)Thoracic678248114103Thoracic: 678 trials, 248 products, 114 approved, 103 ideas (with 3 beneath)Other5654520Other: 565 trials, 45 products, 20 approved, 0 ideas (with 2 beneath)Adolescent and young adult2553Adolescent and young adult: 2 trials, 5 products, 5 approved, 3 ideas (with 1 beneath)Acral melanoma488Acral melanoma: 4 trials, 8 products, 8 approved, 0 ideas. Under MelanomaAcute lymphoblastic leukaemia50514320Acute lymphoblastic leukaemia: 50 trials, 51 products, 43 approved, 20 ideas (with 6 beneath). Under Leukaemia (all types)Acute myeloid leukaemia7156427Acute myeloid leukaemia: 71 trials, 56 products, 42 approved, 7 ideas (with 7 beneath). Under Leukaemia (all types)Acute myeloid leukaemia in children71414Acute myeloid leukaemia in children: 7 trials, 14 products, 14 approved, 0 ideas. Under Acute myeloid leukaemia and PaediatricAcute myeloid leukaemia in older or…1313131Acute myeloid leukaemia in older or unfit patients: 13 trials, 13 products, 13 approved, 1 ideas. Under Acute myeloid leukaemiaAcute promyelocytic leukaemia155Acute promyelocytic leukaemia: 1 trials, 5 products, 5 approved, 0 ideas. Under Acute myeloid leukaemiaAdenoid cystic carcinoma265Adenoid cystic carcinoma: 2 trials, 6 products, 5 approved, 0 ideas. Under Salivary gland cancersAdolescent and young adult cancers…2553Adolescent and young adult cancers (ages 15 to 39): 2 trials, 5 products, 5 approved, 3 ideas. Under Adolescent and young adultAdrenocortical carcinoma299Adrenocortical carcinoma: 2 trials, 9 products, 9 approved, 0 ideas (with 2 beneath). Under EndocrineAdult granulosa cell tumour of the…44Adult granulosa cell tumour of the ovary: 0 trials, 4 products, 4 approved, 0 ideas. Under Ovarian cancerAdvanced and metastatic adrenocorti…99Advanced and metastatic adrenocortical carcinoma (ENSAT stage IV or unresectable): 0 trials, 9 products, 9 approved, 0 ideas. Under Adrenocortical carcinomaAdvanced and metastatic small bowel…96Advanced and metastatic small bowel adenocarcinoma: 0 trials, 9 products, 6 approved, 0 ideas. Under Small intestine cancer (small bowel adenocarcinoma)Advanced cutaneous squamous cell ca…587Advanced cutaneous squamous cell carcinoma: 5 trials, 8 products, 7 approved, 0 ideas. Under Cutaneous squamous cell carcinomaAdvanced hepatocellular carcinoma (…461513Advanced hepatocellular carcinoma (BCLC C): 46 trials, 15 products, 13 approved, 0 ideas. Under Hepatocellular carcinomaAdvanced melanoma (unresectable sta…502216Advanced melanoma (unresectable stage III and stage IV): 50 trials, 22 products, 16 approved, 0 ideas. Under MelanomaAdvanced or recurrent endometrial c…221613Advanced or recurrent endometrial cancer: 22 trials, 16 products, 13 approved, 0 ideas. Under Endometrial cancerAdvanced systemic mastocytosis (agg…265Advanced systemic mastocytosis (aggressive SM, SM with an associated haematological neoplasm, mast cell leukaemia): 2 trials, 6 products, 5 approved, 0 ideas. Under Systemic mastocytosisAdvanced-stage classical Hodgkin ly…6661Advanced-stage classical Hodgkin lymphoma (stage III to IV): 6 trials, 6 products, 6 approved, 1 ideas. Under Hodgkin lymphomaALK-positive non-small-cell lung ca…121091ALK-positive non-small-cell lung cancer: 12 trials, 10 products, 9 approved, 1 ideas. Under Non-small-cell lung cancerAlveolar soft part sarcoma254Alveolar soft part sarcoma: 2 trials, 5 products, 4 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Ampullary cancer (ampulla of Vater)197Ampullary cancer (ampulla of Vater): 1 trials, 9 products, 7 approved, 0 ideas. Under Biliary tract cancer (all types)Anal cancer (squamous cell carcinom…61010Anal cancer (squamous cell carcinoma): 6 trials, 10 products, 10 approved, 0 ideas (with 3 beneath). Under Squamous cell carcinoma and GastrointestinalAnal high-grade squamous intraepith…122Anal high-grade squamous intraepithelial lesions (precursor): 1 trials, 2 products, 2 approved, 0 ideas. Under Anal cancer (squamous cell carcinoma)Anaplastic thyroid cancer66Anaplastic thyroid cancer: 0 trials, 6 products, 6 approved, 0 ideas. Under Thyroid cancerAngiosarcoma298Angiosarcoma: 2 trials, 9 products, 8 approved, 0 ideas. Under Vascular tumours (angiosarcoma, epithelioid haemangioendothelioma, kaposiform haemangioendothelioma)Appendiceal adenocarcinoma (mucinou…64Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell): 0 trials, 6 products, 4 approved, 0 ideas. Under Appendiceal cancer and pseudomyxoma peritonei and AdenocarcinomaAppendiceal cancer and pseudomyxoma…175Appendiceal cancer and pseudomyxoma peritonei: 1 trials, 7 products, 5 approved, 0 ideas (with 3 beneath). Under GastrointestinalAstrocytoma, IDH-mutant (grades 2 t…987Astrocytoma, IDH-mutant (grades 2 to 4): 9 trials, 8 products, 7 approved, 0 ideas. Under Glioma & glioblastomaAtypical teratoid/rhabdoid tumour (…266Atypical teratoid/rhabdoid tumour (ATRT): 2 trials, 6 products, 6 approved, 0 ideas. Under Brain and spinal cord tumours (all types) and PaediatricBasal cell carcinoma997Basal cell carcinoma: 9 trials, 9 products, 7 approved, 0 ideas (with 1 beneath). Under Skin cancer (all types)Biliary tract cancer (all types)5637218Biliary tract cancer (all types): 56 trials, 37 products, 21 approved, 8 ideas (with 3 beneath). Under GastrointestinalBiliary tract cancer (cholangiocarc…5329158Biliary tract cancer (cholangiocarcinoma): 53 trials, 29 products, 15 approved, 8 ideas (with 2 beneath). Under Biliary tract cancer (all types)Biochemical recurrence of prostate…4431Biochemical recurrence of prostate cancer: 4 trials, 4 products, 3 approved, 1 ideas. Under Prostate cancerBladder & urothelial cancer106582819Bladder & urothelial cancer: 106 trials, 58 products, 28 approved, 19 ideas (with 2 beneath). Under GenitourinaryBlastic plasmacytoid dendritic cell…133Blastic plasmacytoid dendritic cell neoplasm (BPDCN): 1 trials, 3 products, 3 approved, 0 ideas. Under Leukaemia (all types)Borderline resectable pancreatic du…5762Borderline resectable pancreatic ductal adenocarcinoma: 5 trials, 7 products, 6 approved, 2 ideas. Under Pancreatic ductal adenocarcinomaBRAF V600-mutant melanoma1413121BRAF V600-mutant melanoma: 14 trials, 13 products, 12 approved, 1 ideas. Under MelanomaBRAF V600E-mutant colorectal cancer61211BRAF V600E-mutant colorectal cancer: 6 trials, 12 products, 11 approved, 0 ideas. Under Colorectal cancerBRAF V600E-mutant non-small-cell lu…288BRAF V600E-mutant non-small-cell lung cancer: 2 trials, 8 products, 8 approved, 0 ideas. Under Non-small-cell lung cancerBrain and spinal cord tumours (all…115776031Brain and spinal cord tumours (all types): 115 trials, 77 products, 60 approved, 31 ideas (with 11 beneath). Under Central nervous systemBrain metastases (secondary brain t…121010Brain metastases (secondary brain tumours): 12 trials, 10 products, 10 approved, 0 ideas. Under Brain and spinal cord tumours (all types)BRCA or PALB2-mutant pancreatic duc…411101BRCA or PALB2-mutant pancreatic ductal adenocarcinoma: 4 trials, 11 products, 10 approved, 1 ideas. Under Pancreatic ductal adenocarcinomaBreast cancer (all types)25916287123Breast cancer (all types): 259 trials, 162 products, 87 approved, 123 ideas (with 9 beneath). Under BreastBuccal mucosa and gingivobuccal can…677Buccal mucosa and gingivobuccal cancer (oral cancer in India): 6 trials, 7 products, 7 approved, 0 ideas. Under Oral cavity cancer (mouth and tongue)Burkitt lymphoma366Burkitt lymphoma: 3 trials, 6 products, 6 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Cancer of unknown primary (CUP)21110Cancer of unknown primary (CUP): 2 trials, 11 products, 10 approved, 0 ideas (with 2 beneath). Under OtherCancer of unknown primary, favourab…77Cancer of unknown primary, favourable subsets: 0 trials, 7 products, 7 approved, 0 ideas. Under Cancer of unknown primary (CUP)Cancer of unknown primary, unfavour…254Cancer of unknown primary, unfavourable (adenocarcinoma and poorly differentiated carcinoma): 2 trials, 5 products, 4 approved, 0 ideas. Under Cancer of unknown primary (CUP) and AdenocarcinomaCentral nervous system germ cell tu…255Central nervous system germ cell tumours (germinoma and non-germinomatous): 2 trials, 5 products, 5 approved, 0 ideas. Under Brain and spinal cord tumours (all types) and Germ cell tumoursCervical cancer63332130Cervical cancer: 63 trials, 33 products, 21 approved, 30 ideas (with 3 beneath). Under GynaecologicChildhood cancers (all types)45353317Childhood cancers (all types): 45 trials, 35 products, 33 approved, 17 ideas (with 7 beneath). Under PaediatricChildhood lung and airway tumours (…44Childhood lung and airway tumours (pleuropulmonary blastoma, tracheobronchial tumours): 0 trials, 4 products, 4 approved, 0 ideas. Under Childhood cancers (all types)Chondrosarcoma244Chondrosarcoma: 2 trials, 4 products, 4 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Chordoma254Chordoma: 2 trials, 5 products, 4 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Chromophobe renal cell carcinoma44Chromophobe renal cell carcinoma: 0 trials, 4 products, 4 approved, 0 ideas. Under Renal cell carcinomaChronic lymphocytic leukaemia6536275Chronic lymphocytic leukaemia: 65 trials, 36 products, 27 approved, 5 ideas (with 3 beneath). Under Leukaemia (all types)Chronic lymphocytic leukaemia, firs…2312112Chronic lymphocytic leukaemia, first treatment: 23 trials, 12 products, 11 approved, 2 ideas. Under Chronic lymphocytic leukaemiaChronic myeloid leukaemia (CML)152119Chronic myeloid leukaemia (CML): 15 trials, 21 products, 19 approved, 0 ideas (with 2 beneath). Under Leukaemia (all types)Chronic myeloid leukaemia, accelera…31313Chronic myeloid leukaemia, accelerated and blast phase: 3 trials, 13 products, 13 approved, 0 ideas. Under Chronic myeloid leukaemia (CML)Chronic myeloid leukaemia, chronic…1087Chronic myeloid leukaemia, chronic phase: 10 trials, 8 products, 7 approved, 0 ideas. Under Chronic myeloid leukaemia (CML)Chronic myelomonocytic leukaemia an…7106Chronic myelomonocytic leukaemia and MDS/MPN overlap neoplasms: 7 trials, 10 products, 6 approved, 0 ideas. Under Leukaemia (all types)Claudin 18.2-positive gastric cancer61171Claudin 18.2-positive gastric cancer: 6 trials, 11 products, 7 approved, 1 ideas. Under Gastric & gastro-oesophageal junction cancerClear cell ovarian cancer133Clear cell ovarian cancer: 1 trials, 3 products, 3 approved, 0 ideas. Under Ovarian cancerClear cell renal cell carcinoma1699Clear cell renal cell carcinoma: 16 trials, 9 products, 9 approved, 0 ideas. Under Renal cell carcinomaColorectal cancer2271024780Colorectal cancer: 227 trials, 102 products, 47 approved, 80 ideas (with 6 beneath). Under GastrointestinalCraniopharyngioma166Craniopharyngioma: 1 trials, 6 products, 6 approved, 0 ideas. Under Brain and spinal cord tumours (all types) and PaediatricCutaneous squamous cell carcinoma91210Cutaneous squamous cell carcinoma: 9 trials, 12 products, 10 approved, 0 ideas (with 1 beneath). Under Squamous cell carcinoma and Skin cancer (all types)Cutaneous T-cell lymphoma (mycosis…3108Cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome): 3 trials, 10 products, 8 approved, 0 ideas. Under Peripheral T-cell lymphomas (including cutaneous T-cell lymphoma)Dermatofibrosarcoma protuberans44Dermatofibrosarcoma protuberans: 0 trials, 4 products, 4 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST) and SkinDesmoid tumour4541Desmoid tumour: 4 trials, 5 products, 4 approved, 1 ideas. Under Sarcomas (soft tissue, bone, GIST)Diffuse large B-cell lymphoma81613818Diffuse large B-cell lymphoma: 81 trials, 61 products, 38 approved, 18 ideas. Under Non-Hodgkin lymphoma (all types)Diffuse midline glioma, H3 K27-alte…922Diffuse midline glioma, H3 K27-altered (including DIPG): 9 trials, 2 products, 2 approved, 0 ideas. Under Glioma & glioblastoma and PaediatricDuctal carcinoma in situ (DCIS)343Ductal carcinoma in situ (DCIS): 3 trials, 4 products, 3 approved, 0 ideas. Under Breast cancer (all types)Early cervical cancer and fertility…3111Early cervical cancer and fertility-sparing surgery: 3 trials, 1 products, 1 approved, 1 ideas. Under Cervical cancerEarly gastric cancer1Early gastric cancer: 1 trials, 0 products, 0 approved, 0 ideas. Under Gastric & gastro-oesophageal junction cancerEarly hepatocellular carcinoma (BCL…8332Early hepatocellular carcinoma (BCLC 0 and A): 8 trials, 3 products, 3 approved, 2 ideas. Under Hepatocellular carcinomaEarly HER2-positive breast cancer2299Early HER2-positive breast cancer: 22 trials, 9 products, 9 approved, 0 ideas. Under HER2-positive breast cancerEarly triple-negative breast cancer131010Early triple-negative breast cancer: 13 trials, 10 products, 10 approved, 0 ideas. Under Triple-negative breast cancer (TNBC)Early-onset colorectal cancer (unde…41093Early-onset colorectal cancer (under 50): 4 trials, 10 products, 9 approved, 3 ideas. Under Colorectal cancerEarly-stage classical Hodgkin lymph…266Early-stage classical Hodgkin lymphoma (stage I to II): 2 trials, 6 products, 6 approved, 0 ideas. Under Hodgkin lymphomaEGFR-mutated non-small-cell lung ca…9419141EGFR-mutated non-small-cell lung cancer: 94 trials, 19 products, 14 approved, 1 ideas. Under Non-small-cell lung cancerEndometrial cancer7332178Endometrial cancer: 73 trials, 32 products, 17 approved, 8 ideas (with 6 beneath). Under GynaecologicEndometrial cancer with no specific…710101Endometrial cancer with no specific molecular profile: 7 trials, 10 products, 10 approved, 1 ideas. Under Endometrial cancerEpendymoma344Ependymoma: 3 trials, 4 products, 4 approved, 0 ideas. Under Brain and spinal cord tumours (all types) and PaediatricEpithelioid haemangioendothelioma55Epithelioid haemangioendothelioma: 0 trials, 5 products, 5 approved, 0 ideas. Under Vascular tumours (angiosarcoma, epithelioid haemangioendothelioma, kaposiform haemangioendothelioma)Epithelioid sarcoma433Epithelioid sarcoma: 4 trials, 3 products, 3 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Erdheim-Chester disease66Erdheim-Chester disease: 0 trials, 6 products, 6 approved, 0 ideas. Under Erdheim-Chester disease, Rosai-Dorfman disease and other histiocytic neoplasmsErdheim-Chester disease, Rosai-Dorf…1111Erdheim-Chester disease, Rosai-Dorfman disease and other histiocytic neoplasms: 0 trials, 11 products, 11 approved, 0 ideas (with 2 beneath). Under HaematologicEssential thrombocythaemia (ET)585Essential thrombocythaemia (ET): 5 trials, 8 products, 5 approved, 0 ideas. Under Myeloproliferative neoplasms (PV, ET, myelofibrosis)Esthesioneuroblastoma (olfactory ne…55Esthesioneuroblastoma (olfactory neuroblastoma): 0 trials, 5 products, 5 approved, 0 ideas. Under Nasal cavity and paranasal sinus cancers (including esthesioneuroblastoma)Ewing sarcoma101412Ewing sarcoma: 10 trials, 14 products, 12 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST) and PaediatricExtensive-stage small-cell lung can…4415122Extensive-stage small-cell lung cancer: 44 trials, 15 products, 12 approved, 2 ideas. Under Small-cell lung cancerExtragonadal germ cell tumour255Extragonadal germ cell tumour: 2 trials, 5 products, 5 approved, 0 ideas. Under Germ cell tumours and GenitourinaryExtrahepatic cholangiocarcinoma (pe…787Extrahepatic cholangiocarcinoma (perihilar and distal): 7 trials, 8 products, 7 approved, 0 ideas. Under Biliary tract cancer (cholangiocarcinoma)Extrapulmonary neuroendocrine carci…41712Extrapulmonary neuroendocrine carcinoma: 4 trials, 17 products, 12 approved, 0 ideas. Under Neuroendocrine tumoursFLT3-mutated acute myeloid leukaemia1066FLT3-mutated acute myeloid leukaemia: 10 trials, 6 products, 6 approved, 0 ideas. Under Acute myeloid leukaemiaFollicular lymphoma452820Follicular lymphoma: 45 trials, 28 products, 20 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Follicular thyroid cancer33Follicular thyroid cancer: 0 trials, 3 products, 3 approved, 0 ideas. Under Thyroid cancerGallbladder cancer898Gallbladder cancer: 8 trials, 9 products, 8 approved, 0 ideas. Under Biliary tract cancer (all types)Gastric & gastro-oesophageal juncti…99633334Gastric & gastro-oesophageal junction cancer: 99 trials, 63 products, 33 approved, 34 ideas (with 5 beneath). Under GastrointestinalGastrointestinal stromal tumour (GI…12106Gastrointestinal stromal tumour (GIST): 12 trials, 10 products, 6 approved, 0 ideas (with 3 beneath). Under Sarcomas (soft tissue, bone, GIST) and GastrointestinalGerm cell tumours of childhood and…266Germ cell tumours of childhood and adolescence (extracranial and CNS): 2 trials, 6 products, 6 approved, 0 ideas. Under Childhood cancers (all types) and Germ cell tumoursGestational trophoblastic neoplasia199Gestational trophoblastic neoplasia: 1 trials, 9 products, 9 approved, 0 ideas (with 3 beneath). Under GynaecologicGlioma & glioblastoma81392630Glioma & glioblastoma: 81 trials, 39 products, 26 approved, 30 ideas (with 5 beneath). Under Brain and spinal cord tumours (all types)Goblet cell adenocarcinoma of the a…31Goblet cell adenocarcinoma of the appendix: 0 trials, 3 products, 1 approved, 0 ideas. Under Appendiceal cancer and pseudomyxoma peritonei and AdenocarcinomaGrade 3 well-differentiated neuroen…3751Grade 3 well-differentiated neuroendocrine tumour: 3 trials, 7 products, 5 approved, 1 ideas. Under Neuroendocrine tumoursGroup 3 and group 4 medulloblastoma…311111Group 3 and group 4 medulloblastoma (non-WNT/non-SHH): 3 trials, 11 products, 11 approved, 1 ideas. Under MedulloblastomaHairy cell leukaemia88Hairy cell leukaemia: 0 trials, 8 products, 8 approved, 0 ideas. Under Leukaemia (all types)Head and neck squamous cell carcino…119532236Head and neck squamous cell carcinoma: 119 trials, 53 products, 22 approved, 36 ideas (with 5 beneath). Under Squamous cell carcinoma and Head and neckHepatoblastoma366Hepatoblastoma: 3 trials, 6 products, 6 approved, 0 ideas. Under Childhood cancers (all types)Hepatocellular carcinoma91302123Hepatocellular carcinoma: 91 trials, 30 products, 21 approved, 23 ideas (with 3 beneath). Under GastrointestinalHER2-amplified colorectal cancer1087HER2-amplified colorectal cancer: 10 trials, 8 products, 7 approved, 0 ideas. Under Colorectal cancerHER2-low and HER2-ultralow metastat…1077HER2-low and HER2-ultralow metastatic breast cancer: 10 trials, 7 products, 7 approved, 0 ideas. Under Breast cancer (all types)HER2-mutant non-small-cell lung can…2698HER2-mutant non-small-cell lung cancer: 26 trials, 9 products, 8 approved, 0 ideas. Under Non-small-cell lung cancerHER2-positive breast cancer91402420HER2-positive breast cancer: 91 trials, 40 products, 24 approved, 20 ideas (with 2 beneath). Under Breast cancer (all types)HER2-positive breast cancer with br…811111HER2-positive breast cancer with brain metastases: 8 trials, 11 products, 11 approved, 1 ideas. Under HER2-positive breast cancerHER2-positive gastric cancer211312HER2-positive gastric cancer: 21 trials, 13 products, 12 approved, 0 ideas. Under Gastric & gastro-oesophageal junction cancerHereditary pheochromocytoma and par…122Hereditary pheochromocytoma and paraganglioma (SDHx, VHL, RET, NF1, MAX and TMEM127): 1 trials, 2 products, 2 approved, 0 ideas. Under Pheochromocytoma and paraganglioma (PPGL)High-grade serous ovarian cancer1488High-grade serous ovarian cancer: 14 trials, 8 products, 8 approved, 0 ideas. Under Ovarian cancerHigh-risk acute lymphoblastic leuka…51918High-risk acute lymphoblastic leukaemia in children (high-risk B-ALL and T-ALL): 5 trials, 19 products, 18 approved, 0 ideas. Under Acute lymphoblastic leukaemia and PaediatricHigh-risk early HR-positive breast…181412High-risk early HR-positive breast cancer: 18 trials, 14 products, 12 approved, 0 ideas. Under HR-positive / HER2-negative breast cancerHigh-risk gestational trophoblastic…99High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk): 0 trials, 9 products, 9 approved, 0 ideas. Under Gestational trophoblastic neoplasiaHigh-risk neuroblastoma920192High-risk neuroblastoma: 9 trials, 20 products, 19 approved, 2 ideas. Under Neuroblastoma (paediatric)Higher-risk myelodysplastic syndrom…8117Higher-risk myelodysplastic syndromes: 8 trials, 11 products, 7 approved, 0 ideas. Under Myelodysplastic syndromes / neoplasms (MDS)HIV-associated (AIDS-related) lymph…11414HIV-associated (AIDS-related) lymphomas: 1 trials, 14 products, 14 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Hodgkin lymphoma52362214Hodgkin lymphoma: 52 trials, 36 products, 22 approved, 14 ideas (with 4 beneath). Under HaematologicHPV-associated vulvar squamous cell…466HPV-associated vulvar squamous cell carcinoma: 4 trials, 6 products, 6 approved, 0 ideas. Under Squamous cell carcinoma and Vulvar cancerHPV-independent vulvar squamous cel…266HPV-independent vulvar squamous cell carcinoma (p53-mutant): 2 trials, 6 products, 6 approved, 0 ideas. Under Squamous cell carcinoma and Vulvar cancerHPV-negative head and neck squamous…13117HPV-negative head and neck squamous cell carcinoma (including HPV-negative oropharyngeal cancer): 13 trials, 11 products, 7 approved, 0 ideas. Under Head and neck squamous cell carcinomaHPV-positive oropharyngeal cancer11542HPV-positive oropharyngeal cancer: 11 trials, 5 products, 4 approved, 2 ideas. Under Oropharyngeal cancer (tonsil and base of tongue)HR-positive / HER2-negative breast…1241166680HR-positive / HER2-negative breast cancer: 124 trials, 116 products, 66 approved, 80 ideas (with 2 beneath). Under Breast cancer (all types)HR-positive metastatic breast cance…252217HR-positive metastatic breast cancer after CDK4/6 inhibitors: 25 trials, 22 products, 17 approved, 0 ideas. Under HR-positive / HER2-negative breast cancerHypopharyngeal cancer566Hypopharyngeal cancer: 5 trials, 6 products, 6 approved, 0 ideas. Under Laryngeal and hypopharyngeal cancerIDH1- and IDH2-mutated acute myeloi…566IDH1- and IDH2-mutated acute myeloid leukaemia: 5 trials, 6 products, 6 approved, 0 ideas. Under Acute myeloid leukaemiaImatinib-resistant GIST574Imatinib-resistant GIST: 5 trials, 7 products, 4 approved, 0 ideas. Under Gastrointestinal stromal tumour (GIST)Indolent and smouldering systemic m…353Indolent and smouldering systemic mastocytosis: 3 trials, 5 products, 3 approved, 0 ideas. Under Systemic mastocytosisInfant acute lymphoblastic leukaemi…212121Infant acute lymphoblastic leukaemia (KMT2A-rearranged, under one year): 2 trials, 12 products, 12 approved, 1 ideas. Under Acute lymphoblastic leukaemia and PaediatricInflammatory breast cancer41212Inflammatory breast cancer: 4 trials, 12 products, 12 approved, 0 ideas. Under Breast cancer (all types)Inflammatory myofibroblastic tumour…88Inflammatory myofibroblastic tumour (IMT): 0 trials, 8 products, 8 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Intermediate hepatocellular carcino…1266Intermediate hepatocellular carcinoma (BCLC B): 12 trials, 6 products, 6 approved, 0 ideas. Under Hepatocellular carcinomaIntermediate-risk neuroblastoma1441Intermediate-risk neuroblastoma: 1 trials, 4 products, 4 approved, 1 ideas. Under Neuroblastoma (paediatric)Intraductal papillary mucinous neop…2215Intraductal papillary mucinous neoplasm and other pancreatic cystic precursors: 2 trials, 2 products, 1 approved, 5 ideas. Under Pancreatic ductal adenocarcinomaIntrahepatic cholangiocarcinoma121081Intrahepatic cholangiocarcinoma: 12 trials, 10 products, 8 approved, 1 ideas. Under Biliary tract cancer (cholangiocarcinoma)Kaposi sarcoma11111Kaposi sarcoma: 1 trials, 11 products, 11 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST) and SkinKIT exon 11-mutant GIST174KIT exon 11-mutant GIST: 1 trials, 7 products, 4 approved, 0 ideas. Under Gastrointestinal stromal tumour (GIST)KRAS G12C-mutant colorectal cancer151811KRAS G12C-mutant colorectal cancer: 15 trials, 18 products, 11 approved, 0 ideas. Under Colorectal cancerKRAS G12C-mutant non-small-cell lun…3314112KRAS G12C-mutant non-small-cell lung cancer: 33 trials, 14 products, 11 approved, 2 ideas. Under Non-small-cell lung cancerKRAS G12C-mutant pancreatic ductal…7118KRAS G12C-mutant pancreatic ductal adenocarcinoma: 7 trials, 11 products, 8 approved, 0 ideas. Under Pancreatic ductal adenocarcinomaKRAS wild-type pancreatic ductal ad…211101KRAS wild-type pancreatic ductal adenocarcinoma: 2 trials, 11 products, 10 approved, 1 ideas. Under Pancreatic ductal adenocarcinomaLangerhans cell histiocytosis (LCH)155Langerhans cell histiocytosis (LCH): 1 trials, 5 products, 5 approved, 0 ideas (with 2 beneath). Under PaediatricLaryngeal and hypopharyngeal cancer566Laryngeal and hypopharyngeal cancer: 5 trials, 6 products, 6 approved, 0 ideas (with 1 beneath). Under Head and neck squamous cell carcinomaLeiomyosarcoma377Leiomyosarcoma: 3 trials, 7 products, 7 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Leukaemia (all types)19413510131Leukaemia (all types): 194 trials, 135 products, 101 approved, 31 ideas (with 7 beneath). Under HaematologicLimited-stage small-cell lung cancer9992Limited-stage small-cell lung cancer: 9 trials, 9 products, 9 approved, 2 ideas. Under Small-cell lung cancerLip cancer233Lip cancer: 2 trials, 3 products, 3 approved, 0 ideas. Under Oral cavity cancer (mouth and tongue)Liposarcoma443Liposarcoma: 4 trials, 4 products, 3 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Localised adrenocortical carcinoma…233Localised adrenocortical carcinoma (ENSAT stage I to III, resectable): 2 trials, 3 products, 3 approved, 0 ideas. Under Adrenocortical carcinomaLocalised anal squamous cell carcin…144Localised anal squamous cell carcinoma (stage I to III): 1 trials, 4 products, 4 approved, 0 ideas. Under Anal cancer (squamous cell carcinoma)Localised penile cancer (organ-conf…122Localised penile cancer (organ-confined, node-negative): 1 trials, 2 products, 2 approved, 0 ideas. Under Penile cancerLocalised prostate cancer, high and…1265Localised prostate cancer, high and very high risk: 12 trials, 6 products, 5 approved, 0 ideas. Under Prostate cancerLocalised prostate cancer, intermed…532Localised prostate cancer, intermediate risk: 5 trials, 3 products, 2 approved, 0 ideas. Under Prostate cancerLocalised prostate cancer, very low…521Localised prostate cancer, very low and low risk: 5 trials, 2 products, 1 approved, 0 ideas. Under Prostate cancerLocalised small bowel adenocarcinom…131Localised small bowel adenocarcinoma (stage I to III, resected): 1 trials, 3 products, 1 approved, 0 ideas. Under Small intestine cancer (small bowel adenocarcinoma)Locally advanced and metastatic bas…843Locally advanced and metastatic basal cell carcinoma: 8 trials, 4 products, 3 approved, 0 ideas. Under Basal cell carcinomaLocally advanced cervical cancer8441Locally advanced cervical cancer: 8 trials, 4 products, 4 approved, 1 ideas. Under Cervical cancerLocally advanced unresectable pancr…11982Locally advanced unresectable pancreatic ductal adenocarcinoma: 11 trials, 9 products, 8 approved, 2 ideas. Under Pancreatic ductal adenocarcinomaLocoregionally advanced nasopharyng…254Locoregionally advanced nasopharyngeal carcinoma (stage III to IVA): 2 trials, 5 products, 4 approved, 0 ideas. Under Nasopharyngeal carcinomaLow-grade appendiceal mucinous neop…32Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei: 0 trials, 3 products, 2 approved, 0 ideas. Under Appendiceal cancer and pseudomyxoma peritoneiLow-grade serous ovarian cancer255Low-grade serous ovarian cancer: 2 trials, 5 products, 5 approved, 0 ideas. Under Ovarian cancerLow-risk gestational trophoblastic…177Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6): 1 trials, 7 products, 7 approved, 0 ideas. Under Gestational trophoblastic neoplasiaLow-risk neuroblastoma (INRG very l…331Low-risk neuroblastoma (INRG very low and low risk, including stage MS): 0 trials, 3 products, 3 approved, 1 ideas. Under Neuroblastoma (paediatric)Lower-risk myelodysplastic syndromes866Lower-risk myelodysplastic syndromes: 8 trials, 6 products, 6 approved, 0 ideas. Under Myelodysplastic syndromes / neoplasms (MDS)Lung cancer (all types)65623510694Lung cancer (all types): 656 trials, 235 products, 106 approved, 94 ideas (with 2 beneath). Under ThoracicLung neuroendocrine tumours (typica…676Lung neuroendocrine tumours (typical and atypical carcinoid): 6 trials, 7 products, 6 approved, 0 ideas. Under Neuroendocrine tumours and LungMale breast cancer21111Male breast cancer: 2 trials, 11 products, 11 approved, 0 ideas. Under Breast cancer (all types)Malignant peripheral nerve sheath t…155Malignant peripheral nerve sheath tumour (MPNST): 1 trials, 5 products, 5 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Mantle cell lymphoma312115Mantle cell lymphoma: 31 trials, 21 products, 15 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Marginal zone lymphoma566Marginal zone lymphoma: 5 trials, 6 products, 6 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Medullary thyroid cancer444Medullary thyroid cancer: 4 trials, 4 products, 4 approved, 0 ideas. Under Thyroid cancerMedulloblastoma616161Medulloblastoma: 6 trials, 16 products, 16 approved, 1 ideas (with 3 beneath). Under Brain and spinal cord tumours (all types) and PaediatricMelanoma137683545Melanoma: 137 trials, 68 products, 35 approved, 45 ideas (with 7 beneath). Under Skin cancer (all types)Meningioma153Meningioma: 1 trials, 5 products, 3 approved, 0 ideas. Under Brain and spinal cord tumours (all types)Merkel cell carcinoma1177Merkel cell carcinoma: 11 trials, 7 products, 7 approved, 0 ideas. Under Skin cancer (all types)Mesothelioma241189Mesothelioma: 24 trials, 11 products, 8 approved, 9 ideas (with 2 beneath). Under ThoracicMET exon 14 and MET-amplified non-s…201211MET exon 14 and MET-amplified non-small-cell lung cancer: 20 trials, 12 products, 11 approved, 0 ideas. Under Non-small-cell lung cancerMetastatic and recurrent anal squam…366Metastatic and recurrent anal squamous cell carcinoma: 3 trials, 6 products, 6 approved, 0 ideas. Under Anal cancer (squamous cell carcinoma)Metastatic cancer (cancer that has…5633511Metastatic cancer (cancer that has spread): 563 trials, 35 products, 11 approved, 0 ideas. Under OtherMetastatic castration-resistant pro…742514Metastatic castration-resistant prostate cancer: 74 trials, 25 products, 14 approved, 0 ideas. Under Prostate cancerMetastatic hormone-sensitive prosta…211010Metastatic hormone-sensitive prostate cancer: 21 trials, 10 products, 10 approved, 0 ideas. Under Prostate cancerMetastatic pancreatic ductal adenoc…7025132Metastatic pancreatic ductal adenocarcinoma: 70 trials, 25 products, 13 approved, 2 ideas. Under Pancreatic ductal adenocarcinomaMetastatic pheochromocytoma and par…387Metastatic pheochromocytoma and paraganglioma: 3 trials, 8 products, 7 approved, 0 ideas. Under Pheochromocytoma and paraganglioma (PPGL)Metastatic triple-negative breast c…411614Metastatic triple-negative breast cancer: 41 trials, 16 products, 14 approved, 0 ideas. Under Triple-negative breast cancer (TNBC)Microsatellite-unstable (MSI-high)…465Microsatellite-unstable (MSI-high) gastric cancer: 4 trials, 6 products, 5 approved, 0 ideas. Under Gastric & gastro-oesophageal junction cancerMismatch repair deficient (MSI-high…2661Mismatch repair deficient (MSI-high) pancreatic ductal adenocarcinoma: 2 trials, 6 products, 6 approved, 1 ideas. Under Pancreatic ductal adenocarcinomaMismatch-repair deficient (MSI-high…19973Mismatch-repair deficient (MSI-high) colorectal cancer: 19 trials, 9 products, 7 approved, 3 ideas. Under Colorectal cancerMismatch-repair-deficient endometri…11552Mismatch-repair-deficient endometrial cancer: 11 trials, 5 products, 5 approved, 2 ideas. Under Endometrial cancerMucinous ovarian cancer55Mucinous ovarian cancer: 0 trials, 5 products, 5 approved, 0 ideas. Under Ovarian cancerMucoepidermoid carcinoma154Mucoepidermoid carcinoma: 1 trials, 5 products, 4 approved, 0 ideas. Under Salivary gland cancersMucosal melanoma31312Mucosal melanoma: 3 trials, 13 products, 12 approved, 0 ideas. Under MelanomaMultiple endocrine neoplasia syndro…188Multiple endocrine neoplasia syndromes (MEN1, MEN2, MEN4): 1 trials, 8 products, 8 approved, 0 ideas. Under EndocrineMultiple myeloma141583917Multiple myeloma: 141 trials, 58 products, 39 approved, 17 ideas (with 5 beneath). Under HaematologicMultisystem Langerhans cell histioc…155Multisystem Langerhans cell histiocytosis (with or without risk-organ involvement): 1 trials, 5 products, 5 approved, 0 ideas. Under Langerhans cell histiocytosis (LCH)Muscle-invasive and advanced bladde…4977Muscle-invasive and advanced bladder cancer: 49 trials, 7 products, 7 approved, 0 ideas. Under Bladder & urothelial cancerMyelodysplastic syndromes / neoplas…312719Myelodysplastic syndromes / neoplasms (MDS): 31 trials, 27 products, 19 approved, 0 ideas (with 2 beneath). Under HaematologicMyeloproliferative neoplasms (PV, E…4127152Myeloproliferative neoplasms (PV, ET, myelofibrosis): 41 trials, 27 products, 15 approved, 2 ideas (with 3 beneath). Under HaematologicMyxofibrosarcoma44Myxofibrosarcoma: 0 trials, 4 products, 4 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Nasal cavity and paranasal sinus ca…88Nasal cavity and paranasal sinus cancers (including esthesioneuroblastoma): 0 trials, 8 products, 8 approved, 0 ideas (with 2 beneath). Under Head and neckNasopharyngeal carcinoma151611Nasopharyngeal carcinoma: 15 trials, 16 products, 11 approved, 0 ideas (with 2 beneath). Under Head and neckNeuroblastoma (paediatric)14222117Neuroblastoma (paediatric): 14 trials, 22 products, 21 approved, 17 ideas (with 3 beneath). Under Childhood cancers (all types)Neuroendocrine and small-cell prost…119Neuroendocrine and small-cell prostate cancer: 0 trials, 11 products, 9 approved, 0 ideas. Under Neuroendocrine tumours and Prostate cancerNeuroendocrine tumours33362411Neuroendocrine tumours: 33 trials, 36 products, 24 approved, 11 ideas (with 5 beneath). Under Neuroendocrine tumours and EndocrineNewly diagnosed multiple myeloma, t…9772Newly diagnosed multiple myeloma, transplant-eligible: 9 trials, 7 products, 7 approved, 2 ideas. Under Multiple myelomaNewly diagnosed multiple myeloma, t…999Newly diagnosed multiple myeloma, transplant-ineligible: 9 trials, 9 products, 9 approved, 0 ideas. Under Multiple myelomaNode-positive and metastatic penile…266Node-positive and metastatic penile cancer: 2 trials, 6 products, 6 approved, 0 ideas. Under Penile cancerNodular lymphocyte-predominant Hodg…66Nodular lymphocyte-predominant Hodgkin lymphoma (nodular lymphocyte-predominant B-cell lymphoma): 0 trials, 6 products, 6 approved, 0 ideas. Under Hodgkin lymphomaNon-Hodgkin lymphoma (all types)2371127918Non-Hodgkin lymphoma (all types): 237 trials, 112 products, 79 approved, 18 ideas (with 11 beneath). Under HaematologicNon-metastatic castration-resistant…344Non-metastatic castration-resistant prostate cancer: 3 trials, 4 products, 4 approved, 0 ideas. Under Prostate cancerNon-muscle-invasive bladder cancer3476Non-muscle-invasive bladder cancer: 34 trials, 7 products, 6 approved, 0 ideas. Under Bladder & urothelial cancerNon-seminomatous germ cell tumour233Non-seminomatous germ cell tumour: 2 trials, 3 products, 3 approved, 0 ideas. Under Testicular germ cell tumoursNon-small-cell lung cancer5732229888Non-small-cell lung cancer: 573 trials, 222 products, 98 approved, 88 ideas (with 12 beneath). Under Lung cancer (all types) and LungNPM1-mutated and KMT2A-rearranged a…765NPM1-mutated and KMT2A-rearranged acute myeloid leukaemia: 7 trials, 6 products, 5 approved, 0 ideas. Under Acute myeloid leukaemiaNTRK fusion-positive non-small-cell…466NTRK fusion-positive non-small-cell lung cancer: 4 trials, 6 products, 6 approved, 0 ideas. Under Non-small-cell lung cancerNUT carcinoma (midline carcinoma wi…343NUT carcinoma (midline carcinoma with NUTM1 rearrangement): 3 trials, 4 products, 3 approved, 0 ideas. Under Head and neckOesophageal and junctional adenocar…141110Oesophageal and junctional adenocarcinoma: 14 trials, 11 products, 10 approved, 0 ideas. Under Oesophageal cancer and AdenocarcinomaOesophageal cancer58352025Oesophageal cancer: 58 trials, 35 products, 20 approved, 25 ideas (with 2 beneath). Under GastrointestinalOesophageal squamous cell carcinoma1488Oesophageal squamous cell carcinoma: 14 trials, 8 products, 8 approved, 0 ideas. Under Oesophageal cancer and Squamous cell carcinomaOligodendroglioma, IDH-mutant and 1…576Oligodendroglioma, IDH-mutant and 1p/19q-codeleted: 5 trials, 7 products, 6 approved, 0 ideas. Under Glioma & glioblastomaOral cavity cancer (mouth and tongu…1388Oral cavity cancer (mouth and tongue): 13 trials, 8 products, 8 approved, 0 ideas (with 3 beneath). Under Head and neck squamous cell carcinomaOral tongue and floor of mouth canc…544Oral tongue and floor of mouth cancer: 5 trials, 4 products, 4 approved, 0 ideas. Under Oral cavity cancer (mouth and tongue)Oropharyngeal cancer (tonsil and ba…15652Oropharyngeal cancer (tonsil and base of tongue): 15 trials, 6 products, 5 approved, 2 ideas (with 1 beneath). Under Head and neck squamous cell carcinomaOsteosarcoma111612Osteosarcoma: 11 trials, 16 products, 12 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST) and PaediatricOvarian cancer154713019Ovarian cancer: 154 trials, 71 products, 30 approved, 19 ideas (with 7 beneath). Under Gynaecologicp53-abnormal endometrial cancer, in…6881p53-abnormal endometrial cancer, including uterine serous carcinoma: 6 trials, 8 products, 8 approved, 1 ideas. Under Endometrial cancerPaediatric high-grade glioma (exclu…21111Paediatric high-grade glioma (excluding diffuse midline glioma): 2 trials, 11 products, 11 approved, 0 ideas. Under Glioma & glioblastoma and PaediatricPaediatric low-grade glioma477Paediatric low-grade glioma: 4 trials, 7 products, 7 approved, 0 ideas. Under Glioma & glioblastoma and PaediatricPaget disease of the nipple22Paget disease of the nipple: 0 trials, 2 products, 2 approved, 0 ideas. Under Breast cancer (all types)Pancreatic acinar cell carcinoma88Pancreatic acinar cell carcinoma: 0 trials, 8 products, 8 approved, 0 ideas. Under Pancreatic ductal adenocarcinomaPancreatic ductal adenocarcinoma164933861Pancreatic ductal adenocarcinoma: 164 trials, 93 products, 38 approved, 61 ideas (with 11 beneath). Under Adenocarcinoma and GastrointestinalPancreatic neuroendocrine tumours131381Pancreatic neuroendocrine tumours: 13 trials, 13 products, 8 approved, 1 ideas. Under Neuroendocrine tumoursPancreatoblastoma33Pancreatoblastoma: 0 trials, 3 products, 3 approved, 0 ideas. Under Pancreatic ductal adenocarcinomaPapillary renal cell carcinoma444Papillary renal cell carcinoma: 4 trials, 4 products, 4 approved, 0 ideas. Under Renal cell carcinomaPapillary thyroid cancer77Papillary thyroid cancer: 0 trials, 7 products, 7 approved, 0 ideas. Under Thyroid cancerParathyroid carcinoma11Parathyroid carcinoma: 0 trials, 1 products, 1 approved, 0 ideas. Under EndocrinePD-L1-high gastric cancer71281PD-L1-high gastric cancer: 7 trials, 12 products, 8 approved, 1 ideas. Under Gastric & gastro-oesophageal junction cancerPD-L1-high non-small-cell lung canc…2714141PD-L1-high non-small-cell lung cancer without a driver mutation: 27 trials, 14 products, 14 approved, 1 ideas. Under Non-small-cell lung cancerPDGFRA D842V-mutant GIST243PDGFRA D842V-mutant GIST: 2 trials, 4 products, 3 approved, 0 ideas. Under Gastrointestinal stromal tumour (GIST)Penile cancer377Penile cancer: 3 trials, 7 products, 7 approved, 0 ideas (with 2 beneath). Under GenitourinaryPeripheral T-cell lymphomas (includ…252621Peripheral T-cell lymphomas (including cutaneous T-cell lymphoma): 25 trials, 26 products, 21 approved, 0 ideas (with 1 beneath). Under Non-Hodgkin lymphoma (all types)Peritoneal mesothelioma2441Peritoneal mesothelioma: 2 trials, 4 products, 4 approved, 1 ideas. Under Mesothelioma and GastrointestinalPerivascular epithelioid cell tumou…255Perivascular epithelioid cell tumour (PEComa): 2 trials, 5 products, 5 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Pheochromocytoma and paraganglioma…587Pheochromocytoma and paraganglioma (PPGL): 5 trials, 8 products, 7 approved, 0 ideas (with 2 beneath). Under EndocrinePhiladelphia chromosome-like acute…255Philadelphia chromosome-like acute lymphoblastic leukaemia (Ph-like or BCR::ABL1-like ALL): 2 trials, 5 products, 5 approved, 0 ideas. Under Acute lymphoblastic leukaemia and PaediatricPhiladelphia chromosome-positive ac…311111Philadelphia chromosome-positive acute lymphoblastic leukaemia in children (Ph-positive ALL): 3 trials, 11 products, 11 approved, 1 ideas. Under Acute lymphoblastic leukaemia and PaediatricPhyllodes tumour of the breast11Phyllodes tumour of the breast: 0 trials, 1 products, 1 approved, 0 ideas. Under Breast cancer (all types)Pituitary tumours (pituitary neuroe…1109Pituitary tumours (pituitary neuroendocrine tumours) and pituitary carcinoma: 1 trials, 10 products, 9 approved, 0 ideas. Under Brain and spinal cord tumours (all types) and Neuroendocrine tumours and EndocrinePlacental-site trophoblastic tumour…66Placental-site trophoblastic tumour and epithelioid trophoblastic tumour: 0 trials, 6 products, 6 approved, 0 ideas. Under Gestational trophoblastic neoplasiaPlasma cell leukaemia1212Plasma cell leukaemia: 0 trials, 12 products, 12 approved, 0 ideas. Under Multiple myelomaPlatinum-resistant ovarian cancer341291Platinum-resistant ovarian cancer: 34 trials, 12 products, 9 approved, 1 ideas. Under Ovarian cancerPlatinum-sensitive ovarian cancer20981Platinum-sensitive ovarian cancer: 20 trials, 9 products, 8 approved, 1 ideas. Under Ovarian cancerPleural mesothelioma7541Pleural mesothelioma: 7 trials, 5 products, 4 approved, 1 ideas. Under MesotheliomaPOLE-ultramutated endometrial cancer4441POLE-ultramutated endometrial cancer: 4 trials, 4 products, 4 approved, 1 ideas. Under Endometrial cancerPolycythaemia vera (PV)131172Polycythaemia vera (PV): 13 trials, 11 products, 7 approved, 2 ideas. Under Myeloproliferative neoplasms (PV, ET, myelofibrosis)Post-transplant lymphoproliferative…288Post-transplant lymphoproliferative disorder (PTLD): 2 trials, 8 products, 8 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Primary CNS lymphoma498Primary CNS lymphoma: 4 trials, 9 products, 8 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types) and Central nervous systemPrimary mediastinal (thymic) large…51313Primary mediastinal (thymic) large B-cell lymphoma: 5 trials, 13 products, 13 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Primary myelofibrosis131511Primary myelofibrosis: 13 trials, 15 products, 11 approved, 0 ideas. Under Myeloproliferative neoplasms (PV, ET, myelofibrosis)Prostate cancer194894861Prostate cancer: 194 trials, 89 products, 48 approved, 61 ideas (with 8 beneath). Under GenitourinaryRare cancers of childhood (NCI PDQ…443Rare cancers of childhood (NCI PDQ umbrella): 4 trials, 4 products, 3 approved, 0 ideas. Under Childhood cancers (all types)Rectal cancer121071Rectal cancer: 12 trials, 10 products, 7 approved, 1 ideas. Under Colorectal cancerRecurrent and metastatic nasopharyn…12138Recurrent and metastatic nasopharyngeal carcinoma: 12 trials, 13 products, 8 approved, 0 ideas. Under Nasopharyngeal carcinomaRecurrent or metastatic cervical ca…2214141Recurrent or metastatic cervical cancer: 22 trials, 14 products, 14 approved, 1 ideas. Under Cervical cancerRecurrent or metastatic head and ne…401711Recurrent or metastatic head and neck squamous cell carcinoma: 40 trials, 17 products, 11 approved, 0 ideas. Under Head and neck squamous cell carcinomaRelapsed and refractory acute lymph…121414Relapsed and refractory acute lymphoblastic leukaemia in children: 12 trials, 14 products, 14 approved, 0 ideas. Under Acute lymphoblastic leukaemia and PaediatricRelapsed and refractory classical H…4661Relapsed and refractory classical Hodgkin lymphoma: 4 trials, 6 products, 6 approved, 1 ideas. Under Hodgkin lymphomaRelapsed or refractory chronic lymp…291110Relapsed or refractory chronic lymphocytic leukaemia: 29 trials, 11 products, 10 approved, 0 ideas. Under Chronic lymphocytic leukaemiaRelapsed or refractory multiple mye…8217151Relapsed or refractory multiple myeloma: 82 trials, 17 products, 15 approved, 1 ideas. Under Multiple myelomaRenal cell carcinoma67332019Renal cell carcinoma: 67 trials, 33 products, 20 approved, 19 ideas (with 3 beneath). Under GenitourinaryResectable pancreatic ductal adenoc…11753Resectable pancreatic ductal adenocarcinoma: 11 trials, 7 products, 5 approved, 3 ideas. Under Pancreatic ductal adenocarcinomaResectable stage I to III non-small…5511113Resectable stage I to III non-small-cell lung cancer: 55 trials, 11 products, 11 approved, 3 ideas. Under Non-small-cell lung cancerRET fusion-positive non-small-cell…655RET fusion-positive non-small-cell lung cancer: 6 trials, 5 products, 5 approved, 0 ideas. Under Non-small-cell lung cancerRetinoblastoma166Retinoblastoma: 1 trials, 6 products, 6 approved, 0 ideas. Under Childhood cancers (all types)Retroperitoneal sarcoma266Retroperitoneal sarcoma: 2 trials, 6 products, 6 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Rhabdomyosarcoma31110Rhabdomyosarcoma: 3 trials, 11 products, 10 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST) and PaediatricRichter transformation of chronic l…277Richter transformation of chronic lymphocytic leukaemia: 2 trials, 7 products, 7 approved, 0 ideas. Under Chronic lymphocytic leukaemiaROS1-positive non-small-cell lung c…1077ROS1-positive non-small-cell lung cancer: 10 trials, 7 products, 7 approved, 0 ideas. Under Non-small-cell lung cancerRosai-Dorfman-Destombes disease44Rosai-Dorfman-Destombes disease: 0 trials, 4 products, 4 approved, 0 ideas. Under Erdheim-Chester disease, Rosai-Dorfman disease and other histiocytic neoplasmsSalivary duct carcinoma11111Salivary duct carcinoma: 1 trials, 11 products, 11 approved, 0 ideas. Under Salivary gland cancersSalivary gland cancers51917Salivary gland cancers: 5 trials, 19 products, 17 approved, 0 ideas (with 3 beneath). Under Head and neckSarcomas (soft tissue, bone, GIST)84947037Sarcomas (soft tissue, bone, GIST): 84 trials, 94 products, 70 approved, 37 ideas (with 24 beneath). Under SarcomaSecondary and therapy-related acute…3981Secondary and therapy-related acute myeloid leukaemia: 3 trials, 9 products, 8 approved, 1 ideas. Under Acute myeloid leukaemiaSeminoma44Seminoma: 0 trials, 4 products, 4 approved, 0 ideas. Under Testicular germ cell tumoursSHH-activated medulloblastoma11111SHH-activated medulloblastoma: 1 trials, 11 products, 11 approved, 0 ideas. Under MedulloblastomaSingle-system Langerhans cell histi…155Single-system Langerhans cell histiocytosis (bone, skin or one other organ): 1 trials, 5 products, 5 approved, 0 ideas. Under Langerhans cell histiocytosis (LCH)Sinonasal undifferentiated carcinom…66Sinonasal undifferentiated carcinoma (SNUC) and SWI/SNF-deficient sinonasal carcinoma: 0 trials, 6 products, 6 approved, 0 ideas. Under Nasal cavity and paranasal sinus cancers (including esthesioneuroblastoma)Skin cancer (all types)162854945Skin cancer (all types): 162 trials, 85 products, 49 approved, 45 ideas (with 4 beneath). Under SkinSmall intestinal neuroendocrine tum…131172Small intestinal neuroendocrine tumours: 13 trials, 11 products, 7 approved, 2 ideas. Under Neuroendocrine tumoursSmall intestine cancer (small bowel…196Small intestine cancer (small bowel adenocarcinoma): 1 trials, 9 products, 6 approved, 0 ideas (with 2 beneath). Under Adenocarcinoma and GastrointestinalSmall-cell lung cancer36741207Small-cell lung cancer: 367 trials, 41 products, 20 approved, 7 ideas (with 2 beneath). Under Lung cancer (all types) and LungSmouldering multiple myeloma655Smouldering multiple myeloma: 6 trials, 5 products, 5 approved, 0 ideas. Under Multiple myelomaSoft tissue sarcoma of the extremit…588Soft tissue sarcoma of the extremity (localised and advanced): 5 trials, 8 products, 8 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Spinal cord tumours (intramedullary…22Spinal cord tumours (intramedullary and intradural): 0 trials, 2 products, 2 approved, 0 ideas. Under Brain and spinal cord tumours (all types)Stage IIB and IIC melanoma4321Stage IIB and IIC melanoma: 4 trials, 3 products, 2 approved, 1 ideas. Under MelanomaStage III melanoma (after surgery)161081Stage III melanoma (after surgery): 16 trials, 10 products, 8 approved, 1 ideas. Under MelanomaStandard-risk B-cell acute lymphobl…214131Standard-risk B-cell acute lymphoblastic leukaemia in children: 2 trials, 14 products, 13 approved, 1 ideas. Under Acute lymphoblastic leukaemia and PaediatricSynovial sarcoma365Synovial sarcoma: 3 trials, 6 products, 5 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Systemic mastocytosis586Systemic mastocytosis: 5 trials, 8 products, 6 approved, 0 ideas (with 2 beneath). Under HaematologicTenosynovial giant cell tumour (TGC…764Tenosynovial giant cell tumour (TGCT): 7 trials, 6 products, 4 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Testicular germ cell tumours31010Testicular germ cell tumours: 3 trials, 10 products, 10 approved, 0 ideas (with 2 beneath). Under Germ cell tumours and GenitourinaryThymic carcinoma31210Thymic carcinoma: 3 trials, 12 products, 10 approved, 0 ideas. Under Thymoma and thymic carcinomaThymoma (WHO types A, AB, B1, B2 an…2119Thymoma (WHO types A, AB, B1, B2 and B3): 2 trials, 11 products, 9 approved, 0 ideas. Under Thymoma and thymic carcinomaThymoma and thymic carcinoma31311Thymoma and thymic carcinoma: 3 trials, 13 products, 11 approved, 0 ideas (with 2 beneath). Under ThoracicThyroid cancer19211811Thyroid cancer: 19 trials, 21 products, 18 approved, 11 ideas (with 4 beneath). Under EndocrineTriple-negative breast cancer (TNBC)90502741Triple-negative breast cancer (TNBC): 90 trials, 50 products, 27 approved, 41 ideas (with 2 beneath). Under Breast cancer (all types)Undifferentiated pleomorphic sarcom…377Undifferentiated pleomorphic sarcoma (UPS): 3 trials, 7 products, 7 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST)Unresectable stage III non-small-ce…1488Unresectable stage III non-small-cell lung cancer: 14 trials, 8 products, 8 approved, 0 ideas. Under Non-small-cell lung cancerUrethral cancer65Urethral cancer: 0 trials, 6 products, 5 approved, 0 ideas. Under GenitourinaryUterine carcinosarcoma3771Uterine carcinosarcoma: 3 trials, 7 products, 7 approved, 1 ideas. Under Endometrial cancerUterine sarcoma51212Uterine sarcoma: 5 trials, 12 products, 12 approved, 0 ideas. Under Sarcomas (soft tissue, bone, GIST) and GynaecologicUveal melanoma1675Uveal melanoma: 16 trials, 7 products, 5 approved, 0 ideas. Under MelanomaVaginal adenocarcinoma (including D…44Vaginal adenocarcinoma (including DES-associated clear cell adenocarcinoma): 0 trials, 4 products, 4 approved, 0 ideas. Under Adenocarcinoma and Vaginal cancerVaginal cancer666Vaginal cancer: 6 trials, 6 products, 6 approved, 0 ideas (with 2 beneath). Under GynaecologicVaginal squamous cell carcinoma (HP…466Vaginal squamous cell carcinoma (HPV-associated): 4 trials, 6 products, 6 approved, 0 ideas. Under Squamous cell carcinoma and Vaginal cancerVascular tumours (angiosarcoma, epi…51211Vascular tumours (angiosarcoma, epithelioid haemangioendothelioma, kaposiform haemangioendothelioma): 5 trials, 12 products, 11 approved, 0 ideas (with 2 beneath). Under Sarcomas (soft tissue, bone, GIST)Vestibular schwannoma (acoustic neu…122Vestibular schwannoma (acoustic neuroma): 1 trials, 2 products, 2 approved, 0 ideas. Under Brain and spinal cord tumours (all types)Vulvar cancer598Vulvar cancer: 5 trials, 9 products, 8 approved, 0 ideas (with 2 beneath). Under GynaecologicWaldenström macroglobulinaemia61111Waldenström macroglobulinaemia: 6 trials, 11 products, 11 approved, 0 ideas. Under Non-Hodgkin lymphoma (all types)Wilms tumour (nephroblastoma)377Wilms tumour (nephroblastoma): 3 trials, 7 products, 7 approved, 0 ideas. Under Childhood cancers (all types)WNT-activated medulloblastoma355WNT-activated medulloblastoma: 3 trials, 5 products, 5 approved, 0 ideas. Under MedulloblastomaAdenocarcinoma1801054661Adenocarcinoma: 180 trials, 105 products, 46 approved, 61 ideas (with 7 beneath)Squamous cell carcinoma150673536Squamous cell carcinoma: 150 trials, 67 products, 35 approved, 36 ideas (with 7 beneath)Neuroendocrine tumours34493411Neuroendocrine tumours: 34 trials, 49 products, 34 approved, 11 ideas (with 3 beneath)Germ cell tumours51212Germ cell tumours: 5 trials, 12 products, 12 approved, 0 ideas (with 4 beneath)
Organ systemHistology groupingCancerSubtypesystem to cancerparent to subtypehistology to cancerbadge grows with the count

The four layers4

Organ system15

The group field on each record: haematologic, gastrointestinal, lung and the rest. Links to the browser filtered to that system.

Histology grouping4

Words in the record names that cut across organs: adenocarcinoma, squamous, neuroendocrine, germ cell. Kept only where members span two or more systems.

Cancer53

Cancers with no broader parent recorded.

Subtype275

Cancers with a parent field; a subtype can also carry its own organ system.

Under more than one node47

These cancers have two or more parents on the map: a site and a lineage, an age group and a disease, or a histology word shared across organs. Each chip names the cancer and the nodes it sits under.

The map as a list347

The same graph as nested lists, one per grouping axis. A cancer that sits under two nodes appears under both, marked ×2. Counts are trials linked to the cancer or anything beneath it.

How the map is built

Every node and edge is read from fields already on the cancer records; nothing is inferred about the diseases themselves. The organ-system layer is the group field. The parent layer is the parent field, the broader cancer a page is a subtype of. The histology layer matches a short fixed vocabulary of words in the record names (adenocarcinoma, squamous, neuroendocrine, germ cell, and others that did not survive the filter below); the schema has no histology field, so this axis is only as complete as the names.

An organ-system or histology edge is left out when a cancer's parent chain already carries the same grouping, so each fact is drawn once. A histology node is kept only when its members span at least two organ systems; otherwise the system node already says the same thing. Layers come from the longest path to each node; within a layer nodes are ordered by repeated barycentre sweeps and then placed at the mean row of their neighbours, which keeps most edges short.

Badge counts are distinct records of each kind linked to a node or anything beneath it: trials and products in either direction of the graph, approved products meaning linked products with at least one recorded approval, and ideas that name the cancer. Pick the badge above; the choice is kept in the address as ?by=.

For scripts and agents: https://onco.cc/cancers/map/graph.json has the nodes, edges, layers and statistics; every cancer node carries the page it links to. The technology dependency map is drawn the same way.