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Oxycodone is a strong painkiller used for cancer pain, often when morphine does not suit, for example with kidney problems or when the medicine has to be given under the skin.
The OxyContin label covers severe and persistent pain that needs an opioid and cannot be adequately treated with alternatives, in adults and some opioid-tolerant children, with boxed warnings on addiction, abuse and respiratory depression. The Australian cancer pain guideline (2025 update) names oxycodone among the preferred opioids in severe kidney disease, with careful titration, and among the opioids to switch to subcutaneously when the oral route is no longer possible. The reformulated OxyContin NDA in Drugs@FDA was approved on 5 April 2010.
A full opioid agonist, acting mainly at the mu-opioid receptor.
1.Oxycodone slips into a pocket on its target.
| Region | Year | Indication |
|---|---|---|
| US | 2010 | Severe and persistent pain requiring an opioid that cannot be adequately treated with alternatives · Year is NDA 022272 (reformulated OxyContin) in Drugs@FDA; the original 1995 application is not in the API and is not dated here |
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Query for this drug: (TITLE:"Oxycodone" OR ABSTRACT:"Oxycodone" OR TITLE:"OxyContin" OR ABSTRACT:"OxyContin" OR TITLE:"OxyNorm" OR ABSTRACT:"OxyNorm" OR TITLE:"oxycodone hydrochloride" OR ABSTRACT:"oxycodone hydrochloride") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Oxycodone, not a curated reading list.
Shares Cancer pain management and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares Cancer pain management and the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
Shares the tags supportive, generic, supportive-care-gaps-2026-11.
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