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Rocapuldencel-T is an individualised autologous dendritic cell immunotherapy from Argos Therapeutics that reached phase 3 for metastatic renal cell carcinoma; development has stopped.
Rocapuldencel-T (AGS-003, AGS-003-LNG, AGS-003-BLD) is an individualised autologous dendritic cell immunotherapy (Arcelis platform) from Argos Therapeutics. An individualised immunotherapy made from the patient's own dendritic cells using the Arcelis platform; registry descriptions call it an RNA-transfected autologous dendritic cell vaccine (renal cell carcinoma/CD40L RNA). Its furthest stage is phase 3, for metastatic renal cell carcinoma. ClinicalTrials.gov registers it in 7 studies linked below. The ADAPT phase 3 IDMC recommended stopping for futility in February 2017; Argos continued, then discontinued ADAPT after an April 2018 interim analysis (10-Q filed 19 Nov 2018). Argos filed for chapter 11 on 30 November 2018 (8-K). Whether it works in people has not been established unless a trial below reports it.
An individualised immunotherapy made from the patient's own dendritic cells using the Arcelis platform; registry descriptions call it an RNA-transfected autologous dendritic cell vaccine (renal cell carcinoma/CD40L RNA).
1.Rocapuldencel-T slips into a pocket on its target.
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Query for this drug: (TITLE:"Rocapuldencel-T" OR ABSTRACT:"Rocapuldencel-T" OR TITLE:"AGS-003" OR ABSTRACT:"AGS-003" OR TITLE:"AGS-003-LNG" OR ABSTRACT:"AGS-003-LNG" OR TITLE:"AGS-003-BLD" OR ABSTRACT:"AGS-003-BLD") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Rocapuldencel-T, not a curated reading list.
Shares Renal cell carcinoma and the tags pipeline, discontinued.
Shares the tags pipeline, discontinued.
Shares the tags pipeline, discontinued.
Shares the tags pipeline, discontinued.
Shares the tags pipeline, discontinued.
Shares the tags pipeline, discontinued.
Shares the tags pipeline, discontinued.
Shares the tags pipeline, discontinued.
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